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Cancerous tumours

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Symptoms, risk and screening
Are you over 50 years old, or have you been having urinary problems for some time now? This video is for you! Several diseases can affect your prostate, and it’s important to detect them early. Let’s take a closer look.

 

Overview

Médecin et patient discutent des résultats de la biopsie et des traitements du cancer de la prostateProstate cancer is a disease that generally progresses at a fairly slow pace and, when detected early, is highly curable. In the majority of cases, when detected at a localized stage, that is to say in the absence of it spreading to other parts of the body (metastasis), the survival rate is excellent. That’s why early detection is important.

Nowadays, advanced techniques are used to produce an extremely accurate diagnosis. In addition, multiple effective therapeutic approaches can halt or slow the progression of the disease. In most cases, the prognosis is encouraging.

Prostate cancer is the most common form of cancer in men. It is sometimes indolent, sometimes fatal and it causes little or no symptoms at first. Although it strikes on average around the age of 67, it can affect men in their forties or fifties. In Quebec, nineteen (19) men are diagnosed daily.

Although the incidence of prostate cancer continues to increase, the latest advances in treatment have reduced the risk of death. Indeed, considerable progress has been made in terms of invasive surgeries or specific radiation therapies to treat certain forms of prostate cancer, which in turn has reduced the risk of complications and has allowed for a faster recovery.

The exact causes of prostate cancer remain largely unknown. However, research has highlighted some risk factors.

Facts and figures

 

Key points

Generally speaking, cancer is characterized by uncontrolled growth of abnormal cells. It can affect any type of cell in an organ, a gland, muscle tissue, blood or the lymphatic system.

Under normal conditions, the cells in our bodies contain all the information they need for their development, function, reproduction and death. Usually, our cells do their work properly and we remain healthy. However, sometimes a few of the cells do not behave normally and begin multiplying uncontrollably, eventually forming a group of abnormal cells. After a while, this group forms a detectable lump known as a tumour.

Over time, the malignant cells in cancerous tumours can invade neighbouring tissue or organs. They may even spread to the rest of the body through the blood or lymphatic system. This stage is known as “metastasis.”

In the case of prostate cancer, the secretory cells are usually the ones that become cancerous. Once the cancer has been diagnosed, treatment is determined depending on the stage of the disease and the overall health of the patient

Types of prostate cancer

Prostate cancer is a very heterogeneous disease, some progress very slowly while others are more aggressive. In reality, most cases are somewhere between the two. For the moment, science does not have the tools to accurately predict the growth rate of a person’s cancer once it has been diagnosed. Clinicians use a variety of information to estimate the speed of the cancer.

About 14 percent of Canadians suffer from “clinical” prostate cancer, meaning their disease has been detected by a doctor and officially diagnosed. However, studies of autopsy reports have shown that another 30 percent of men have latent cancer, mean­ing the cancerous cells lie dormant in the prostate. Although pres­ent, the cancer does no harm because it does not attack the body. Not all men develop latent prostate cancer, but the proba­bility of doing so increases with age.

According to the current state of knowledge, prostate cancer is one of the few cancers that can remain in latent form for such a long period of time. Researchers are trying to understand why some cancers remain latent while others develop into full-blown diseases. While it is generally believed that risk factors and genes play an important role in the development of clinically significant cancer, the precise mechanism is still unknown.

We are here for you

You have questions or concerns? Don’t hesitate. Contact us at 1-855-899-2873 to discuss with one of our nurses specialized in uro-oncology. They are there to listen, support and answer your questions, and those of your family or your loved ones. It’s simple and free, like all of our other services.

Also take the time to visit each of our pages on this website, as well as our YouTube channel, in order to get familiar with the disease, our expert lectures, our section on available resources, the support that is offered to you, our events and ways to get involved to advance the cause.

 

Staying Informed

Pages that might interest you
Want to know more? Just click on one of the links below.

The latest PROCURE news that might interest
Every week we publish a blog article. Here are some we chose for you.

The medical content and editorial team at PROCURE
Our team is composed of urologists, and nurses certified in uro-oncology with a deep knowledge of prostate cancer and other diseases related to the genitourinary system. Meet our staff by clicking here.

Sources and references

Last medical and editorial review: September 2023
Written by PROCURE. © All rights reserved

Cancerous tumours

Cancerous tumours

Cancerous tumors

Prostate cancer is a disease that generally progresses at a fairly slow pace and, when detected early, is highly curable. In the majority of cases, when detected at a localized stage, that is to say in the absence of it spreading to other parts of the body (metastasis), the survival rate is excellent. That’s why early detection is important.
 

Illustration de l’appareil de l’homme pour un cancer prostate

Nowadays, advanced techniques are used to produce an extremely accurate diagnosis. In addition, multiple effective therapeutic approaches can halt or slow the progression of the disease. In most cases, the prognosis is encouraging.

Prostate cancer is the most common form of cancer in men. It is sometimes indolent, sometimes fatal and it causes little or no symptoms at first. Although it strikes on average around the age of 67, it can affect men in their forties or fifties. In Quebec, nineteen (19) men are diagnosed daily.

Although the incidence of prostate cancer continues to increase, the latest advances in treatment have reduced the risk of death. Indeed, considerable progress has been made in terms of invasive surgeries or specific radiation therapies to treat certain forms of prostate cancer, which in turn has reduced the risk of complications and has allowed for a faster recovery.

The exact causes of prostate cancer remain largely unknown. However, research has highlighted some risk factors.

Generally speaking, cancer is characterized by uncontrolled growth of abnormal cells. It can affect any type of cell in an organ, a gland, muscle tissue, blood or the lymphatic system.
 
Under normal conditions, the cells in our bodies contain all the information they need for their development, function, reproduction and death. Usually, our cells do their work properly and we remain healthy. However, sometimes a few of the cells do not behave normally and begin multiplying uncontrollably, eventually forming a group of abnormal cells. After a while, this group forms a detectable lump known as a tumour.
 
Over time, the malignant cells in cancerous tumours can invade neighbouring tissue or organs. They may even spread to the rest of the body through the blood or lymphatic system. This stage is known as “metastasis.”
 
In the case of prostate cancer, the secretory cells are usually the ones that become cancerous. Once the cancer has been diagnosed, treatment is determined depending on the stage of the disease and the overall health of the patient.
 
Types of prostate cancer
 
Prostate cancer is a very heterogeneous disease, some progress very slowly while others are more aggressive. In reality, most cases are somewhere between the two. For the moment, science does not have the tools to accurately predict the growth rate of a person’s cancer once it has been diagnosed. Clinicians use a variety of information to estimate the speed of the cancer.
 
About 14 percent of Canadians suffer from “clinical” prostate cancer, meaning their disease has been detected by a doctor and officially diagnosed. However, studies of autopsy reports have shown that another 30 percent of men have latent cancer, mean­ing the cancerous cells lie dormant in the prostate. Although pres­ent, the cancer does no harm because it does not attack the body. Not all men develop latent prostate cancer, but the proba­bility of doing so increases with age.
 
According to the current state of knowledge, prostate cancer is one of the few cancers that can remain in latent form for such a long period of time. Researchers are trying to understand why some cancers remain latent while others develop into full-blown diseases. While it is generally believed that risk factors and genes play an important role in the development of clinically significant cancer, the precise mechanism is still unknown.

Other pages that might interest you

Additional Information - Prostate diseases

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33min

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Cancer and Nutrition with Dr. Isabelle Huot

This conference provides concrete examples of recommended foods and products for patients.

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Cultivating intimacy during and after prostate cancer

How can couples maintain intimacy during and after prostate cancer treatment? Is it possible to cultivate intimacy?  

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Radical surgery with Kevin Zorn

Learn about robotic radical surgery for prostate cancer and whether it is an option for you.  

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Advanced prostate cancer treatment strategies

Strategies for treating advanced cancer have significantly evolved, offering new options and hope for patients.

Lire l'article

Sources and references
Last medical and editorial review: April 2024. See our web page validation committee and our collaborators by clicking here.

Discover our animated video!

Symptoms, risk and screening
Are you over 50 years old, or have you been having urinary problems for some time now? This video is for you! Several diseases can affect your prostate, and it’s important to detect them early. Let’s take a closer look. 

 

Anatomy

What is the prostate

Illustration de l’appareil de l’homme pour un cancer prostate

The prostate is a gland:

  • Located between the bladder and the penis, just in front of the rectum;
  • Formed of 2 lobes which surround the urethra, a canal that runs through the center of the prostate, from the bladder to the penis, letting urine and sperm flow out of the body;
  • The size of a walnut, which grows larger in size in your forties;
  • That has a soft, spongy texture to the touch like a small, ripe plum.

The prostate is made of:

  • Gland cells that secrete liquids for ejaculation;
  • Muscle cells that participate in the evacuation of your sperm during ejaculation;
  • Fiber cells that maintain the structure of the gland.

Around the prostate, we find:

  • The seminal vesicles, glands that produce sperm and that are located on either side of the prostate;
  • The vas deferens, the tube that carries sperm from the testicle to the seminal vesicles;
  • The nerve bundles that control your bladder and erectile function and that are located on either side of your prostate.

Structure

Three main zones of the prostate

Illustration des 3 zones de la prostate de l’homme cancer prostate

Peripheral zone

  • The peripheral zone is the largest area of the prostate. It can easily be felt by the doctor during a digital rectal exam (DRE).
  • Most prostate cancers start in the peripheral zone.

Transition zone

  • This is the area located in the middle of the prostate, between the peripheral and central areas. It surrounds your urethra that runs through the prostate.
  • With age, the transitional area increases in size until it becomes the largest portion of your prostate. This is called benign prostatic hyperplasia (BPH) or enlarged prostate.

Central zone

  • It is the part of the prostate that is farthest from the rectum. This is why prostate tumors located in this area can not be felt by the doctor during a digital rectal examination.
  • If the doctor is in doubt, the following information will help decide if additional investigation is necessary:
    • Your PSA level
    • Your age and family history
    • Your ethnic origin

Fonction

In short

Illustration d’une prostate saine cancer prostate

Your fertility and natural fertilization

  • It produces … a prostatic fluid rich in enzymes, proteins and minerals that nourishes and protects your spermatozoa.
  • It makes … a protein (APS) that is used to liquefy your sperm to facilitate the mobility of your spermatozoa.
  • It allows … ejaculation by contracting.
  • It promotes … fertility through its enzymes facilitating the penetration of sperm through the cervix.
  • It is not related to the mechanism of erection. Therefore, the origin of erectile dysfunction lies elsewhere.

Additional details

Exocrine Function

The prostate is made up of thousands of tiny fluid-producing glands. Specifically, the prostate is an exocrine gland. Exocrine glands are so-called because they secrete through ducts to the outside of the body (or into a cavity that communicates with the outside). Sweat glands are another example of an exocrine gland.

The fluid that the prostate gland produces forms part of semen, the fluid that carries sperm during orgasm. This fluid, produced in the prostate, is stored with sperm in the seminal vesicles. When the male climaxes, muscular contractions cause the prostate to secrete this fluid into the urethra, where it is expelled from the body through the penis.

Urine Flow

The prostate wraps itself around the urethra as it passes from the bladder to the penis. Prostatic changes can affect urine flow. Increasing the size of the prostate or muscle tone may impede the flow of urine due to the close anatomical relationship between the urethra and the prostate.

Prostate Specific Antigen (PSA)

The prostate also produces a protein called prostate-specific antigen (PSA). PSA is released with the ejaculatory fluid and can also be traced in the bloodstream. The testing of PSA levels in the blood is used to detect prostate cancer. The level of PSA in the blood is usually measured in nanograms of PSA per milliliter of blood (ng/mL).

A raised PSA level

Usually, a PSA rate of less than 4 nanograms per milliliter of blood is normal, but age should also be taken into consideration as PSA levels gradually increase with age. A rise in PSA concentration may indicate the presence of:

  • An enlarged prostate (benign prostatic hyperplasia)
  • An inflammation or infection of the prostate (prostatitis)
  • A prostate cancer

Your doctor will have you undergo other tests to determine the exact cause of the increase in your PSA.

We are here for you

You have questions or concerns? Don’t hesitate. Contact us at 1-855-899-2873 to discuss with one of our nurses specialized in uro-oncology. They are there to listen, support and answer your questions, and those of your family or your loved ones. It’s simple and free, like all of our other services.

Also take the time to visit each of our pages on this website, as well as our YouTube channel, in order to get familiar with the disease, our expert lectures, our section on available resources, the support that is offered to you, our events and ways to get involved to advance the cause..

 

Staying Informed

Pages that might interest you
Want to know more? Just click on one of the links below.

The latest PROCURE news that might interest you
Every week we publish a blog article. Here are some for you.

The medical content and editorial team at PROCURE
Our team is composed of urologists, and nurses certified in uro-oncology with a deep knowledge of prostate cancer and other diseases related to the genitourinary system. Meet our staff by clicking here.

Sources and references

Last medical and editorial review: September 2023
Written by PROCURE. © All rights reserved

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